Sepbox 2D-250

High-throughput screening of compounds from natural sources

Automated separation of compounds from natural sources using 2D HPLC and SPE coupling

A large proportion of pharmaceutical drugs are related to natural products. To assist research into the many promising substances which remain undiscovered or untested, the compact Sepbox series is designed for the automated separation of compounds from natural sources (such as Traditional Chinese Medicines) using 2D HPLC (High Performance Liquid Chromatography) and SPE (Solid Phase Extraction) coupling.

The Sepbox's patented online coupling of HPLC-SPE-HPLC techniques allows samples to be processed automatically for high throughput screening, rapidly generating reproducible and reliable separations. By eliminating the need for a large investment in HR and research facilities, it enables significant savings in time and money to be made.

An automated 2D preparative system for a small benchtop, the 2D-250 provides efficient and reliable separation in a compact unit. Its intuitive user-friendly software supports method development, process control, data acquisition and data analysis.

  • Significantly accelerates the purification process from weeks or months to just hours
  • Handles a wide range of medium to non-polar compounds , with optional polar setup
  • Isolation of compounds from up to 250mg of extracts derived from natural products: plants, marine organisms, microbiological or animal materials, with recovery rates up to 90%
  • Separation of up to 576 fractions within 24 hours
  • Stainless steel for the capillaries
  • Fraction collection of 12 racks with 48 glass vials each for up to 6ml fractions
  • Solid or liquid injection
  • Equipped with UV and optional ELSD detector
  • Sample size: Max. 250mg of extract
  • Pumps: 2 HPLC pumps
  • Dimensions: 170 x 60 x 75 cm (W x D x H)
  • Weight: 150 kg including Fraction Collector
  • Traditional Chinese Medicine and Herbals
  • Agriculture
  • Pharmaceutical
  • Cosmetics
  • Food and Feedstuffs
  • Environmental
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